Meaning: The quote you provided is attributed to Charles Nicolle, a French bacteriologist who was awarded the Nobel Prize in Physiology or Medicine in 1928 for his work on typhus. In this quote, Nicolle is referring to the practical significance of the guinea pig's susceptibility to infection and its role in preserving viruses in laboratory settings.

Nicolle's statement highlights the importance of the guinea pig as a valuable animal model for studying and preserving viruses. The guinea pig's susceptibility to infection proved to be a significant advancement in scientific research, particularly in the field of virology. By using the guinea pig as a host for preserving viruses, laboratories were able to conduct essential experiments and studies on infectious diseases.

Guinea pigs have been extensively used in scientific research due to their physiological and genetic similarities to humans in certain aspects. Their susceptibility to various pathogens, including viruses, has made them a valuable animal model for studying infectious diseases and testing potential treatments and vaccines.

Nicolle's acknowledgment of the guinea pig's role in preserving viruses underscores the animal's importance in advancing our understanding of infectious diseases and developing effective interventions. This recognition also reflects the significant impact that animal models have had on scientific and medical progress throughout history.

In contemporary biomedical research, the use of animal models, including guinea pigs, continues to play a crucial role in studying infectious diseases and developing new treatments. The knowledge gained from studying viruses in guinea pigs has contributed to the development of vaccines and antiviral therapies that have saved countless lives and improved global public health.

It is essential to note that while the use of animal models in research has led to significant scientific advancements, ethical considerations and animal welfare are paramount. Researchers and institutions must adhere to strict ethical guidelines and regulations to ensure the humane treatment of animals in scientific studies.

In conclusion, Charles Nicolle's quote emphasizes the practical significance of the guinea pig's susceptibility to infection in preserving viruses for laboratory research. The use of guinea pigs as animal models has been instrumental in advancing our understanding of infectious diseases and developing interventions to combat them. While animal models continue to be important in scientific research, it is crucial to prioritize ethical considerations in the use of animals for experimentation and to ensure their humane treatment.